The Methylation Cycle

Methylation is a type of gene expression. There are hundreds of different methylation reactions in the body. Most commonly noted is its role in the body’s ability to detoxify. Eighty five to ninety percent of people with autism are known to have reduced methylation. Methylation is required to produce glutathione.  Untitled design (27)

When there is heavy toxic burden on the liver it has a strong demand for the body’s master antioxidant glutathione. When glutathione level drops low enough, the sulfur metabolism becomes disrupted. The methylation cycle (part of the sulfur metabolism, or detoxification) can become partially blocked and deplete some or all of several important sulfur containing metabolites including S-Adenosyl Methionine (SAMe), cysteine, glutathione, taurine, and sulfate. This can create such a weakening in the system that it allows disease to develop.

It is crucial to assist the liver. A few of the many symptoms of methylation disruption are associated with liver disruption. Liver Detoxification Pathway Elixir is an excellent choice for liver support and detoxification. Glutathione can also be taken in supplemental form.

MPR elixir is a liquid sublingual supplement which optimizes the enzymatic activity related to methylation pathway repair and stimulates repair of any damaged DNA controlling the methylation pathway.

Do you or your child have any symptoms of liver and methylation disruption such as:

  • lowered immunity
  • hearing trouble and ear infections
  • headaches
  • depression
  •  irritability
  •  fatigue
  •  ADHD
  • skin problems (itching, acne, hives, rashes)
  • sinus and tonsil issues
  • tooth decay and gum disease
  • viral infections
  • parasites
  • thyroid imbalance
  • protein synthesis
  • respiratory issues
  • poor assimilation of nutrients
  • digestive difficulty

Interviews with Experts on Methylation

Karen’s live radio show interview on methylation with Dr. Bob Miller, on Methylation.

Dr. Miller’s bio (brief):

Bob Miller is a Traditional Naturopath specializing in the field of genetic-specific nutrition. He earned his naturopathic degree from Trinity School of Natural Health and is board certified through the ANMA. In 1993, he opened the Tree of Life practice and he has served as a traditional naturopath for 25 years. For the past several years, he has been engaged exclusively with nutritional genetic variants and related research, specializing in nutritional support for those with chronic Lyme disease.

For consultations or information on Tree of Life, visit or call, (717)733-2003

To find practitioner who does functional genomics visit

For healthcare professionals looking to get into functional genomic nutrition visit

For NutriGenetic Research Institute research projects visit

For upcoming seminars for practitioners, visit

Functional Genomic Analysis software


Karen’s podcast interview with Dr. Richard Deth on the methylation cycle.

Interview with Dr. Stephanie Seneff on Sulfates, radio show #24.

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